Statins Remain a Key Tool in Lowering Stroke Risk; Doctors Say

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Medications work best when paired with healthy habits, according to Novant Health cardiology experts

By BC News Staff

Ischemic stroke is the most common type of stroke in the United States, and it often develops long before symptoms appear. Local cardiology experts say cholesterol management remains one of the strongest ways to reduce that risk — and statin medications continue to play a major role.

Ischemic strokes occur when blood flow to the brain is blocked, typically by plaque buildup inside the arteries. High cholesterol and high blood pressure are two of the leading contributors. Nearly 800,000 ischemic strokes occur nationwide each year.

Statins help lower low‑density lipoprotein (LDL), the “bad” cholesterol, while improving high‑density lipoprotein (HDL), the “good” cholesterol. The medications also help clear plaque that can harden or break loose, restricting blood and oxygen flow to the brain.
Cardiologists note that statins are commonly recommended for patients with a history of stroke, heart disease, diabetes, high blood pressure or a family history of cardiovascular risk. While generally safe, they are not appropriate for everyone, including pregnant women and people with certain liver conditions.

Health providers emphasize that statins work best when combined with daily habits that support cardiovascular health. Those include regular physical activity, a balanced diet, blood‑pressure monitoring and avoiding smoking.
Doctors also continue to address common misconceptions about statins. Research shows no evidence that the medications cause memory loss or dementia, and genetics, not just diet, play a significant role in cholesterol levels. Statins may also be recommended for younger adults depending on their individual risk factors.

Information in this report is based on a March 2026 article by Patrick Flanary for Novant Health.

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